A robust in vivo positive-readout system for monitoring siRNA delivery to xenograft tumors

Delivering small interfering RNA (siRNA) to tumors is the major technical hurdle that prevents the advancement of siRNA-based cancer therapy. One of the difficulties associated with the development of clinically relevant delivery systems is the lack of reliable tools for monitoring siRNA delivery to...

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Main Authors: Lin, Xiaoyu, Li, Leiming, Wang, Rongqi, Wilcox, Denise, Zhao, Xiaobin, Song, Jingfeng, Huang, Xiaoli, Hansen, T. Matthew, Dande, Prasad, Wada, Carol, Hubbard, Robert D., Kohlbrenner, William M., Fesik, Stephen W., Shen, Yu
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062172/
https://ncbi.nlm.nih.gov/pubmed/21321186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2546011
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