Fluid flow shear stress over podocytes is increased in the solitary kidney

BACKGROUND: Glomerular hyperfiltration is emerging as the key risk factor for progression of chronic kidney disease (CKD). Podocytes are exposed to fluid flow shear stress (FFSS) caused by the flow of ultrafiltrate within Bowman's space. The mechanism of hyperfiltration-induced podocyte injury...

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Main Authors: Srivastava, Tarak, Celsi, Gianni E., Sharma, Mukut, Dai, Hongying, McCarthy, Ellen T., Ruiz, Melanie, Cudmore, Patricia A., Alon, Uri S., Sharma, Ram, Savin, Virginia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888310/
https://ncbi.nlm.nih.gov/pubmed/24166460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gft387
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