Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney

Increased fluid flow shear stress (FFSS) in solitary kidney alters podocyte function in vivo. FFSS-treated cultured podocytes show upregulated AKT-GSK3β-β-catenin signaling. The present study was undertaken to confirm (i) the activation of β-catenin signaling in podocytes in vivo using unilaterally...

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Publicat a:Cells
Autors principals: Srivastava, Tarak, Heruth, Daniel P., Duncan, R. Scott, Rezaiekhaligh, Mohammad H., Garola, Robert E., Priya, Lakshmi, Zhou, Jianping, Boinpelly, Varun C., Novak, Jan, Ali, Mohammed Farhan, Joshi, Trupti, Alon, Uri S., Jiang, Yuexu, McCarthy, Ellen T., Savin, Virginia J., Sharma, Ram, Johnson, Mark L., Sharma, Mukut
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159099/
https://ncbi.nlm.nih.gov/pubmed/34069476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051253
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