Fluid flow shear stress over podocytes is increased in the solitary kidney

BACKGROUND: Glomerular hyperfiltration is emerging as the key risk factor for progression of chronic kidney disease (CKD). Podocytes are exposed to fluid flow shear stress (FFSS) caused by the flow of ultrafiltrate within Bowman's space. The mechanism of hyperfiltration-induced podocyte injury...

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Hlavní autoři: Srivastava, Tarak, Celsi, Gianni E., Sharma, Mukut, Dai, Hongying, McCarthy, Ellen T., Ruiz, Melanie, Cudmore, Patricia A., Alon, Uri S., Sharma, Ram, Savin, Virginia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888310/
https://ncbi.nlm.nih.gov/pubmed/24166460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gft387
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