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A Single-Amino-Acid Variant of the H60 CD8 Epitope Generates Specific Immunity with Diverse TCR Recruitment

TCR of CD8 T cells recognizes peptides of 8–9 amino acids in length (epitope) complexed with MHC class I. Peptide ligands differing from an epitope by one or two amino acids are thought to modulate the immune response specific to that epitope. H60 is a minor histocompatibility antigen for which the...

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Bibliografske podrobnosti
Main Authors: Ryu, Su Jeong, Jeon, Ji Yeong, Chang, Jun, Sproule, Thomas J., Roopenian, Derry C., Choi, Eun Young
Format: Artigo
Jezik:Inglês
Izdano: Korea Society for Molecular and Cellular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887807/
https://ncbi.nlm.nih.gov/pubmed/22441676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0008-3
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