Targeted Androgen Pathway Suppression in Localized Prostate Cancer: A Pilot Study

PURPOSE: Ligand-mediated activation of the androgen receptor (AR) is critical for prostate cancer (PCa) survival and proliferation. The failure to completely ablate tissue androgens may limit suppression of PCa growth. We evaluated combinations of CYP17A and 5-α-reductase inhibitors for reducing pro...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mostaghel, Elahe A., Nelson, Peter S., Lange, Paul, Lin, Daniel W., Taplin, Mary Ellen, Balk, Steven, Ellis, William, Kantoff, Philip, Marck, Brett, Tamae, Daniel, Matsumoto, Alvin M., True, Lawrence D., Vessella, Robert, Penning, Trevor, Hunter Merrill, Rachel, Gulati, Roman, Montgomery, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2014
Fag:
ORIGINAL REPORTS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887479/
https://ncbi.nlm.nih.gov/pubmed/24323034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.48.6431
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker