Targeted Androgen Pathway Suppression in Localized Prostate Cancer: A Pilot Study

PURPOSE: Ligand-mediated activation of the androgen receptor (AR) is critical for prostate cancer (PCa) survival and proliferation. The failure to completely ablate tissue androgens may limit suppression of PCa growth. We evaluated combinations of CYP17A and 5-α-reductase inhibitors for reducing pro...

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Bibliografische gegevens
Hoofdauteurs: Mostaghel, Elahe A., Nelson, Peter S., Lange, Paul, Lin, Daniel W., Taplin, Mary Ellen, Balk, Steven, Ellis, William, Kantoff, Philip, Marck, Brett, Tamae, Daniel, Matsumoto, Alvin M., True, Lawrence D., Vessella, Robert, Penning, Trevor, Hunter Merrill, Rachel, Gulati, Roman, Montgomery, Bruce
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887479/
https://ncbi.nlm.nih.gov/pubmed/24323034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.48.6431
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