Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

Aims: Angiotensin II (AngII)-induced superoxide (O(2)(•−)) production by the NADPH oxidases and mitochondria has been implicated in the pathogenesis of endothelial dysfunction and hypertension. In this work, we investigated the specific molecular mechanisms responsible for the stimulation of mitocho...

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Autors principals: Dikalov, Sergey I., Nazarewicz, Rafal R., Bikineyeva, Alfiya, Hilenski, Lula, Lassègue, Bernard, Griendling, Kathy K., Harrison, David G., Dikalova, Anna E.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Forum Original Research CommunicationsMitochondria (A. Daiber, Ed.)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887459/
https://ncbi.nlm.nih.gov/pubmed/24053613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4918
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