Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension

Aims: Angiotensin II (AngII)-induced superoxide (O(2)(•−)) production by the NADPH oxidases and mitochondria has been implicated in the pathogenesis of endothelial dysfunction and hypertension. In this work, we investigated the specific molecular mechanisms responsible for the stimulation of mitocho...

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Detalhes bibliográficos
Main Authors: Dikalov, Sergey I., Nazarewicz, Rafal R., Bikineyeva, Alfiya, Hilenski, Lula, Lassègue, Bernard, Griendling, Kathy K., Harrison, David G., Dikalova, Anna E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Forum Original Research CommunicationsMitochondria (A. Daiber, Ed.)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887459/
https://ncbi.nlm.nih.gov/pubmed/24053613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4918
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