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Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

RATIONALE: Superoxide (O(2)(∸)) has been implicated in the pathogenesis of many human diseases including hypertension, however commonly employed antioxidants have proven ineffective in clinical trials. It is possible that these agents are not adequately delivered to the subcellular sites of superoxi...

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Detalhes bibliográficos
Main Authors: Dikalova, Anna E., Bikineyeva, Alfiya T., Budzyn, Klaudia, Nazarewicz, Rafal R., McCann, Louise, Lewis, William, Harrison, David G., Dikalov, Sergey I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901409/
https://ncbi.nlm.nih.gov/pubmed/20448215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.214601
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