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Nox2 as a potential target of mitochondrial superoxide and its role in endothelial oxidative stress
Superoxide (O(2)(·−)) production by the NADPH oxidases is implicated in the pathogenesis of many cardiovascular diseases, including hypertension. We have previously shown that activation of NADPH oxidases increases mitochondrial O(2)(·−) which is inhibited by the ATP-sensitive K(+) channel (mitoK(AT...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798790/ https://ncbi.nlm.nih.gov/pubmed/23955717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2013 |
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