Nox2 as a potential target of mitochondrial superoxide and its role in endothelial oxidative stress

Superoxide (O(2)(·−)) production by the NADPH oxidases is implicated in the pathogenesis of many cardiovascular diseases, including hypertension. We have previously shown that activation of NADPH oxidases increases mitochondrial O(2)(·−) which is inhibited by the ATP-sensitive K(+) channel (mitoK(AT...

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Bibliographic Details
Main Authors: Nazarewicz, Rafal R., Dikalova, Anna E., Bikineyeva, Alfiya, Dikalov, Sergey I.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798790/
https://ncbi.nlm.nih.gov/pubmed/23955717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2013
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