Distinct Roles of Nox1 and Nox4 in Basal and Angiotensin II-Stimulated Superoxide and Hydrogen Peroxide Production

NADPH oxidases are major sources of superoxide (O(2)(∸)) and hydrogen peroxide (H(2)O(2)) in vascular cells. Production of these reactive oxygen species (ROS) is essential for cell proliferation and differentiation, while ROS overproduction has been implicated in hypertension and atherosclerosis. It...

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Main Authors: Dikalov, Sergey I., Dikalova, Anna E., Bikineyeva, Alfiya T., Schmidt, Harald H.H.W., Harrison, David G., Griendling, Kathy K.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630771/
https://ncbi.nlm.nih.gov/pubmed/18760347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.08.013
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