Defining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor α Ligand Binding Domain

Retinoid X receptors (RXRs) are obligate partners for several other nuclear receptors, and they play a key role in several signaling processes. Despite being a promiscuous heterodimer partner, this nuclear receptor is a target of therapeutic intervention through activation using selective RXR agonis...

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Bibliographic Details
Main Authors: Boerma, LeeAnn J., Xia, Gang, Qui, Cheng, Cox, Bryan D., Chalmers, Michael J., Smith, Craig D., Lobo-Ruppert, Susan, Griffin, Patrick R., Muccio, Donald D., Renfrow, Matthew B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887207/
https://ncbi.nlm.nih.gov/pubmed/24187139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476861
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