Thermodynamic Analysis of the Binding of 2F5 (Fab and Immunoglobulin G Forms) to Its gp41 Epitope Reveals a Strong Influence of the Immunoglobulin Fc Region on Affinity

Immunotherapies and vaccines based on the induction of broadly neutralizing monoclonal antibodies (bNAbs) have become outstanding strategies against HIV-1. Diverse bNAbs recognizing different regions of the HIV-1 envelope have been identified and extensively studied. However, there is little informa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Crespillo, Sara, Casares, Salvador, Mateo, Pedro L., Conejero-Lara, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887187/
https://ncbi.nlm.nih.gov/pubmed/24302742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.524439
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados