Molecular and Physicochemical Factors Governing Solubility of the HIV gp41 Ectodomain

The HIV gp41 ectodomain (e-gp41) is an attractive target for the development of vaccines and drugs against HIV because of its crucial role in viral fusion to the host cell. However, because of the high insolubility of e-gp41, most biophysical and structural analyses have relied on the production of...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Manssour-Triedo, Fadia, Crespillo, Sara, Morel, Bertrand, Casares, Salvador, Mateo, Pedro L., Notka, Frank, Roger, Marie G., Mouz, Nicolas, El-Habib, Raphaelle, Conejero-Lara, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002082/
https://ncbi.nlm.nih.gov/pubmed/27558714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.022
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