Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells

BACKGROUND: Apaf1 (apoptotic protease activating factor 1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. Other cellular roles, including a pro-survival role, have...

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Bibliografiska uppgifter
Huvudupphovsmän: Sancho, Mónica, Gortat, Anna, Herrera, Andrés E., Andreu-Fernández, Vicente, Ferraro, Elisabetta, Cecconi, Francesco, Orzáez, Mar, Pérez-Payá, Enrique
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886985/
https://ncbi.nlm.nih.gov/pubmed/24416260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084666
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