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Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells
BACKGROUND: Apaf1 (apoptotic protease activating factor 1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. Other cellular roles, including a pro-survival role, have...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886985/ https://ncbi.nlm.nih.gov/pubmed/24416260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084666 |
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