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Apaf1 inhibition promotes cell recovery from apoptosis

The protein apoptotic protease activating factor 1 (Apaf1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. We have developed a vital method that allows fluorescence-...

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Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Gortat, Anna, Sancho, Mónica, Mondragón, Laura, Messeguer, Àngel, Pérez-Payá, Enrique, Orzáez, Mar
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624680/
https://ncbi.nlm.nih.gov/pubmed/26361785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0200-2
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