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Magnetic resonance imaging of tumor glycolysis using hyperpolarized (13)C-labeled glucose

Glycolysis in murine lymphoma and lung tumors was monitored by measuring the conversion of hyperpolarized [U-(2)H, U-(13)C]glucose to lactate using (13)C magnetic resonance spectroscopy and spectroscopic imaging. Labeled lactate was only observed in tumors, and not in surrounding normal tissue or in...

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Detalhes bibliográficos
Main Authors: Rodrigues, Tiago B., Serrao, Eva M., Kennedy, Brett W.C., Hu, De-en, Kettunen, Mikko I., Brindle, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886895/
https://ncbi.nlm.nih.gov/pubmed/24317119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3416
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