Hyperpolarized (13)C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

Glioblastoma (GBM) is the most aggressive brain tumor type in adults. GBM is heterogeneous, with a compact core lesion surrounded by an invasive tumor front. This front is highly relevant for tumor recurrence but is generally non-detectable using standard imaging techniques. Recent studies demonstra...

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Pubblicato in:Sci Rep
Autori principali: Mishkovsky, Mor, Gusyatiner, Olga, Lanz, Bernard, Cudalbu, Cristina, Vassallo, Irene, Hamou, Marie-France, Bloch, Jocelyne, Comment, Arnaud, Gruetter, Rolf, Hegi, Monika E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952603/
https://ncbi.nlm.nih.gov/pubmed/33707647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85339-7
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