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In vivo detection of brain Krebs cycle intermediate by hyperpolarized magnetic resonance

The Krebs (or tricarboxylic acid (TCA)) cycle has a central role in the regulation of brain energy regulation and metabolism, yet brain TCA cycle intermediates have never been directly detected in vivo. This study reports the first direct in vivo observation of a TCA cycle intermediate in intact bra...

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Hlavní autoři: Mishkovsky, Mor, Comment, Arnaud, Gruetter, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519415/
https://ncbi.nlm.nih.gov/pubmed/22990416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.136
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