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In vivo detection of brain Krebs cycle intermediate by hyperpolarized magnetic resonance

The Krebs (or tricarboxylic acid (TCA)) cycle has a central role in the regulation of brain energy regulation and metabolism, yet brain TCA cycle intermediates have never been directly detected in vivo. This study reports the first direct in vivo observation of a TCA cycle intermediate in intact bra...

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Detalhes bibliográficos
Main Authors: Mishkovsky, Mor, Comment, Arnaud, Gruetter, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519415/
https://ncbi.nlm.nih.gov/pubmed/22990416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.136
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