Loss of PIAS3 Expression in Glioblastoma Multiforme Tumors: Implications for STAT-3 Activation and Gene Expression

PURPOSE: Signal Transducers and Activators of Transcription (STATs) activate transcription in response to numerous cytokines, controlling proliferation, gene expression and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includ...

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Bibliografische gegevens
Hoofdauteurs: Brantley, Emily C., Nabors, L. Burton, Gillespie, G. Yancey, Choi, Youn-Hee, Palmer, Cheryl Ann, Harrison, Keith, Roarty, Kevin, Benveniste, Etty N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886729/
https://ncbi.nlm.nih.gov/pubmed/18676737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0618
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