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Loss of PIAS3 Expression in Glioblastoma Multiforme Tumors: Implications for STAT-3 Activation and Gene Expression
PURPOSE: Signal Transducers and Activators of Transcription (STATs) activate transcription in response to numerous cytokines, controlling proliferation, gene expression and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886729/ https://ncbi.nlm.nih.gov/pubmed/18676737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0618 |
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