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T cell immunodominance is dictated by the positively selecting self-peptide
Naive T cell precursor frequency determines the magnitude of immunodominance. While a broad T cell repertoire requires diverse positively selecting self-peptides, how a single positively selecting ligand influences naive T cell precursor frequency remains undefined. We generated a transgenic mouse e...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885792/ https://ncbi.nlm.nih.gov/pubmed/24424413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01457 |
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