An endogenous peptide positively selects and augments peripheral CD4(+) T cell activation and survival

Although CD4(+) and CD8(+) T cells differ in their positively selecting signal strength, endogenous positively selecting ligands have only been identified for MHC class I-restricted T cell receptors (TCRs). Here we screened for ligands that can positively select MHC class II-restricted TCRs, using t...

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Bibliografiska uppgifter
Huvudupphovsmän: Lo, Wan-Lin, Felix, Nathan J., Walters, James J., Rohrs, Henry, Gross, Michael L., Allen, Paul M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764840/
https://ncbi.nlm.nih.gov/pubmed/19801984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1796
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