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Self-awareness: How self-peptide/MHC complexes are essential in the development of T cells
The processing and presentation of self-proteins is essential to develop an effective immune system, with almost all T cells only ever encountering self-peptide/MHC ligands. How positive selection in the thymus occurs with a weak interaction between the TCR and self-pMHC remains unresolved. The rece...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594560/ https://ncbi.nlm.nih.gov/pubmed/23196128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.028 |
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