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Self-awareness: How self-peptide/MHC complexes are essential in the development of T cells

The processing and presentation of self-proteins is essential to develop an effective immune system, with almost all T cells only ever encountering self-peptide/MHC ligands. How positive selection in the thymus occurs with a weak interaction between the TCR and self-pMHC remains unresolved. The rece...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lo, Wan-Lin, Allen, Paul M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594560/
https://ncbi.nlm.nih.gov/pubmed/23196128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.028
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