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Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway

Hepatocarcinogenesis commonly involves the gradual progression from hepatitis to fibrosis and cirrhosis, and ultimately to hepatocellular carcinoma (HCC). Endothelin 1 (Edn1) has been identified as a gene that is significantly up-regulated in HBx-induced HCC in mice. In this study, we further invest...

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書誌詳細
主要な著者: Lu, Jeng-Wei, Liao, Chung-Yi, Yang, Wan-Yu, Lin, Yueh-Min, Jin, Shiow-Lian Catherine, Wang, Horng-Dar, Yuh, Chiou-Hwa
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885696/
https://ncbi.nlm.nih.gov/pubmed/24416389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085318
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