Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway

Hepatocarcinogenesis commonly involves the gradual progression from hepatitis to fibrosis and cirrhosis, and ultimately to hepatocellular carcinoma (HCC). Endothelin 1 (Edn1) has been identified as a gene that is significantly up-regulated in HBx-induced HCC in mice. In this study, we further invest...

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Bibliografski detalji
Glavni autori: Lu, Jeng-Wei, Liao, Chung-Yi, Yang, Wan-Yu, Lin, Yueh-Min, Jin, Shiow-Lian Catherine, Wang, Horng-Dar, Yuh, Chiou-Hwa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885696/
https://ncbi.nlm.nih.gov/pubmed/24416389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085318
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