Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway

Hepatocarcinogenesis commonly involves the gradual progression from hepatitis to fibrosis and cirrhosis, and ultimately to hepatocellular carcinoma (HCC). Endothelin 1 (Edn1) has been identified as a gene that is significantly up-regulated in HBx-induced HCC in mice. In this study, we further invest...

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Autors principals: Lu, Jeng-Wei, Liao, Chung-Yi, Yang, Wan-Yu, Lin, Yueh-Min, Jin, Shiow-Lian Catherine, Wang, Horng-Dar, Yuh, Chiou-Hwa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885696/
https://ncbi.nlm.nih.gov/pubmed/24416389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085318
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