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Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway

Hepatocarcinogenesis commonly involves the gradual progression from hepatitis to fibrosis and cirrhosis, and ultimately to hepatocellular carcinoma (HCC). Endothelin 1 (Edn1) has been identified as a gene that is significantly up-regulated in HBx-induced HCC in mice. In this study, we further invest...

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Detalhes bibliográficos
Main Authors: Lu, Jeng-Wei, Liao, Chung-Yi, Yang, Wan-Yu, Lin, Yueh-Min, Jin, Shiow-Lian Catherine, Wang, Horng-Dar, Yuh, Chiou-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885696/
https://ncbi.nlm.nih.gov/pubmed/24416389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085318
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