Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis

BACKGROUND: Patients with ulcerative colitis (UC) are at risk of developing colorectal cancer. We have previously reported that cancer progression is associated with the presence of clonal expansions and shorter telomeres in non-dysplastic mucosa. We sought to validate these findings in an independe...

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Detalhes bibliográficos
Main Authors: Salk, Jesse J., Bansal, Aasthaa, Lai, Lisa A., Crispin, David A., Ussakli, Cigdem H., Horwitz, Marshall S., Bronner, Mary P., Brentnall, Teresa A., Loeb, Lawrence A., Rabinovitch, Peter S., Risques, Rosa Ana
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885330/
https://ncbi.nlm.nih.gov/pubmed/24097228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e3182a87640
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