Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis

BACKGROUND: Patients with ulcerative colitis (UC) are at risk of developing colorectal cancer. We have previously reported that cancer progression is associated with the presence of clonal expansions and shorter telomeres in non-dysplastic mucosa. We sought to validate these findings in an independe...

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Autores principales: Salk, Jesse J., Bansal, Aasthaa, Lai, Lisa A., Crispin, David A., Ussakli, Cigdem H., Horwitz, Marshall S., Bronner, Mary P., Brentnall, Teresa A., Loeb, Lawrence A., Rabinovitch, Peter S., Risques, Rosa Ana
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885330/
https://ncbi.nlm.nih.gov/pubmed/24097228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e3182a87640
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