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Passenger Mutations as a Marker of Clonal Cell Lineages in Emerging Neoplasia
Cancer arises as the result of a natural selection process among cells of the body, favoring lineages bearing somatic mutations that bestow them with a proliferative advantage. Of the thousands of mutations within a tumor, only a small fraction functionally drive its growth; the vast majority are me...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993762/ https://ncbi.nlm.nih.gov/pubmed/20951806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.10.008 |
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