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Clonal expansions in ulcerative colitis identify patients with neoplasia
Chronic inflammation predisposes to a variety of human cancers. Affected tissues slowly accumulate mutations, some of which affect growth regulation and drive successive waves of clonal evolution, whereas a far greater number are functionally neutral and serve only to passively mark expanding clones...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779829/ https://ncbi.nlm.nih.gov/pubmed/19926851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909428106 |
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