Clonal expansions in ulcerative colitis identify patients with neoplasia

Chronic inflammation predisposes to a variety of human cancers. Affected tissues slowly accumulate mutations, some of which affect growth regulation and drive successive waves of clonal evolution, whereas a far greater number are functionally neutral and serve only to passively mark expanding clones...

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Bibliografiska uppgifter
Huvudupphovsmän: Salk, Jesse J., Salipante, Stephen J., Risques, Rosa Ana, Crispin, David A., Li, Lin, Bronner, Mary P., Brentnall, Teresa A., Rabinovitch, Peter S., Horwitz, Marshall S., Loeb, Lawrence A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779829/
https://ncbi.nlm.nih.gov/pubmed/19926851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909428106
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