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miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs
miRNA-mediated repression in animals is dependent on the GW182 protein family. GW182 proteins are recruited to the miRNA repression complex through direct interaction with Argonaute proteins, and they function downstream to repress target mRNA. Here we demonstrate that in human and Drosophila melano...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885283/ https://ncbi.nlm.nih.gov/pubmed/21984184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2166 |
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