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miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs

miRNA-mediated repression in animals is dependent on the GW182 protein family. GW182 proteins are recruited to the miRNA repression complex through direct interaction with Argonaute proteins, and they function downstream to repress target mRNA. Here we demonstrate that in human and Drosophila melano...

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Bibliografische gegevens
Hoofdauteurs: Chekulaeva, Marina, Mathys, Hansruedi, Zipprich, Jakob T, Attig, Jan, Colic, Marija, Parker, Roy, Filipowicz, Witold
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885283/
https://ncbi.nlm.nih.gov/pubmed/21984184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2166
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