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CB(2) Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease

The endocannabinoid CB(2) receptor system has been implicated in the neuropathology of Alzheimer’s disease (AD). In order to investigate the impact of the CB(2) receptor system on AD pathology, a colony of mice with a deleted CB(2) receptor gene, CNR2, was established on a transgenic human mutant AP...

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Hlavní autoři: Koppel, Jeremy, Vingtdeux, Valerie, Marambaud, Philippe, d’Abramo, Cristina, Jimenez, Heidy, Stauber, Mark, Friedman, Rachel, Davies, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883962/
https://ncbi.nlm.nih.gov/pubmed/24408112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00140
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