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CB(2) Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease

The endocannabinoid CB(2) receptor system has been implicated in the neuropathology of Alzheimer’s disease (AD). In order to investigate the impact of the CB(2) receptor system on AD pathology, a colony of mice with a deleted CB(2) receptor gene, CNR2, was established on a transgenic human mutant AP...

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Detalhes bibliográficos
Main Authors: Koppel, Jeremy, Vingtdeux, Valerie, Marambaud, Philippe, d’Abramo, Cristina, Jimenez, Heidy, Stauber, Mark, Friedman, Rachel, Davies, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883962/
https://ncbi.nlm.nih.gov/pubmed/24408112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00140
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