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EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180
Glioblastomas (GBMs), the most common and malignant brain tumors, are highly resistant to current therapies. The failure of targeted therapies against aberrantly activated oncogenic signaling, such as that of the EGFR-PI3K/Akt pathway, underscores the urgent need to understand alternative downstream...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883905/ https://ncbi.nlm.nih.gov/pubmed/23728337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.198 |
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