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Transient reduction of 5-methylcytosine and 5-hydroxymethylcytosine is associated with active DNA demethylation during regeneration of zebrafish fin

Although dedifferentiation, transformation of differentiated cells into progenitor cells, is a critical step in the regeneration of amphibians and fish, the molecular mechanisms underlying this process, including epigenetic changes, remain unclear. Dot blot assays and immunohistochemical analyses re...

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Bibliographic Details
Main Authors: Hirose, Kentaro, Shimoda, Nobuyoshi, Kikuchi, Yutaka
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883767/
https://ncbi.nlm.nih.gov/pubmed/23880758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25653
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