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4-Hydroxy-2-nonenal Enhances Tissue Factor Activity in Human Monocytic Cells via p38 MAPK Activation-dependent Phosphatidylserine Exposure

OBJECTIVE: 4-hydroxy-2-nonenal (HNE) is one of the major aldehydes formed during lipid peroxidation, and is believed to play a role in the pathogenesis of atherosclerosis. The objective of the present study is to investigate the effect of HNE on tissue factor (TF) procoagulant activity expressed on...

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Autors principals: Vatsyayan, Rit, Kothari, Hema, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883589/
https://ncbi.nlm.nih.gov/pubmed/23640483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.300972
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