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Inactivation of Factor VIIa by Antithrombin In Vitro, Ex Vivo and In Vivo: Role of Tissue Factor and Endothelial Cell Protein C Receptor

Recent studies have suggested that antithrombin (AT) could act as a significant physiologic regulator of FVIIa. However, in vitro studies showed that AT could inhibit FVIIa effectively only when it was bound to tissue factor (TF). Circulating blood is known to contain only traces of TF, at best. FVI...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Vatsyayan, Rit, Kothari, Hema, Mackman, Nigel, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125150/
https://ncbi.nlm.nih.gov/pubmed/25102166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103505
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