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Oxidative Stress Product, 4-Hydroxy-2-Nonenal, Induces the Release of Tissue Factor-Positive Microvesicles From Perivascular Cells Into Circulation

TF (Tissue factor) plays a key role in hemostasis, but an aberrant expression of TF leads to thrombosis. The objective of the present study is to investigate the effect of 4-hydroxy-2-nonenal (HNE), the most stable and major oxidant produced in various disease conditions, on the release of TF(+) mic...

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Dettagli Bibliografici
Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Ansari, Shabbir A., Keshava, Shiva, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752210/
https://ncbi.nlm.nih.gov/pubmed/33028097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315187
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