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Stress Hormone Leads to Memory Deficits and Altered Tau Phosphorylation in a Model of Alzheimer’s Disease

Several studies have linked stress with Alzheimer’s disease (AD) vulnerability; however, the mechanism remains to be fully elucidated. In the current paper, we investigated the role of glucocortitcoids on the AD-like phenotype. We administered the glucocorticoid dexamethasone to Tg2576 mice for 4 we...

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Autors principals: Joshi, Yash B., Chu, Jin, Praticò, Domenico
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882896/
https://ncbi.nlm.nih.gov/pubmed/22531419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-120328
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