Transcriptional Intermediary Factor 1γ binds to the Anaphase-Promoting Complex/Cyclosome and promotes mitosis

The Anaphase-Promoting Complex/Cyclosome (APC/C) is an ubiquitin ligase that functions during mitosis. Here we identify the transcriptional regulator, Transcriptional Intermediary Factor 1γ, TIF1γ as an APC/C-interacting protein that regulates APC/C function. TIF1γ is not a substrate for APC/C-depen...

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Autors principals: Sedgwick, Garry G., Townsend, Kelly, Martin, Ashley, Shimwell, Neil J., Grand, Roger J. A., Stewart, Grant S., Nilsson, Jakob, Turnell, Andrew S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882591/
https://ncbi.nlm.nih.gov/pubmed/23160376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.501
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