Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis

In mitosis and meiosis, chromosome segregation is triggered by the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit ubiquitin ligase that targets proteins for degradation, leading to the separation of chromatids. APC/C activation requires phosphorylation of its APC3 and APC1 subunits, w...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Garrido, Damien, Bourouh, Mohammed, Bonneil, Éric, Thibault, Pierre, Swan, Andrew, Archambault, Vincent
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660922/
https://ncbi.nlm.nih.gov/pubmed/33137813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009184
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