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Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis
In mitosis and meiosis, chromosome segregation is triggered by the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit ubiquitin ligase that targets proteins for degradation, leading to the separation of chromatids. APC/C activation requires phosphorylation of its APC3 and APC1 subunits, w...
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7660922/ https://ncbi.nlm.nih.gov/pubmed/33137813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009184 |
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