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Adenovirus E4orf3 Targets Transcriptional Intermediary Factor 1γ for Proteasome-Dependent Degradation during Infection

The ability of adenovirus early region proteins, E1B-55K and E4orf6, to usurp control of cellular ubiquitin ligases and target proteins for proteasome-dependent degradation during infection is well established. Here we show that the E4 gene product, E4orf3 can, independently of E1B-55K and E4orf6, t...

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Detalhes bibliográficos
Main Authors: Forrester, Natalie A., Patel, Rakesh N., Speiseder, Thomas, Groitl, Peter, Sedgwick, Garry G., Shimwell, Neil J., Seed, Robert I., Catnaigh, Pól Ó, McCabe, Christopher J., Stewart, Grant S., Dobner, Thomas, Grand, Roger J. A., Martin, Ashley, Turnell, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302322/
https://ncbi.nlm.nih.gov/pubmed/22205733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06583-11
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