Control of mRNA Export by Adenovirus E4orf6 and E1B55K Proteins during Productive Infection Requires E4orf6 Ubiquitin Ligase Activity

During the adenovirus infectious cycle, the early proteins E4orf6 and E1B55K are known to perform several functions. These include nuclear export of late viral mRNAs, a block of nuclear export of the bulk of cellular mRNAs, and the ubiquitin-mediated degradation of selected proteins, including p53 a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Blanchette, Paola, Kindsmüller, Kathrin, Groitl, Peter, Dallaire, Frédéric, Speiseder, Thomas, Branton, Philip E., Dobner, Thomas
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
Genome Replication and Regulation of Viral Gene Expression
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258987/
https://ncbi.nlm.nih.gov/pubmed/18184699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02309-07
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