Control of mRNA Export by Adenovirus E4orf6 and E1B55K Proteins during Productive Infection Requires E4orf6 Ubiquitin Ligase Activity

During the adenovirus infectious cycle, the early proteins E4orf6 and E1B55K are known to perform several functions. These include nuclear export of late viral mRNAs, a block of nuclear export of the bulk of cellular mRNAs, and the ubiquitin-mediated degradation of selected proteins, including p53 a...

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Detalhes bibliográficos
Main Authors: Blanchette, Paola, Kindsmüller, Kathrin, Groitl, Peter, Dallaire, Frédéric, Speiseder, Thomas, Branton, Philip E., Dobner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258987/
https://ncbi.nlm.nih.gov/pubmed/18184699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02309-07
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