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Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation

We have investigated the requirements for CRM1-mediated nuclear export and SUMO1 conjugation of the adenovirus E1B-55K protein during productive infection. Our data show that CRM1 is the major export receptor for E1B-55K in infected cells. Functional inactivation of the E1B-55K CRM1-dependent nuclea...

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Detalhes bibliográficos
Main Authors: Kindsmüller, Kathrin, Groitl, Peter, Härtl, Barbara, Blanchette, Paola, Hauber, Joachim, Dobner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871846/
https://ncbi.nlm.nih.gov/pubmed/17428914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702158104
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