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The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F

The human adenovirus E4orf6/E1B55K E3 ubiquitin ligase is well known to promote viral replication by degrading an increasing number of cellular proteins that inhibit the efficient production of viral progeny. We report here a new function of the adenovirus 5 (Ad5) viral ligase complex that, although...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Dallaire, Frédéric, Schreiner, Sabrina, Blair, G. Eric, Dobner, Thomas, Branton, Philip E., Blanchette, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863625/
https://ncbi.nlm.nih.gov/pubmed/27303679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00014-15
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