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Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation
Activation of the cellular DNA damage response is detrimental to adenovirus (Ad) infection. Ad has therefore evolved a number of strategies to inhibit ATM- and ATR-dependent signaling pathways during infection. Recent work suggests that the Ad5 E4orf3 protein prevents ATR activation through its abil...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901489/ https://ncbi.nlm.nih.gov/pubmed/20566845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914605107 |
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