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Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2

The cation cotransporters Na(+)-K(+)-2Cl(−) cotransporter 1 and 2 (NKCC1 and NKCC2) and Na(+)-Cl cotransporter (NCC) are phosphorylated and activated by the kinases Ste20-related proline alanine-rich kinase (SPAK) and oxidative stress-responsive kinase (OSR1), and their targeted disruption in mice c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Park, Hae J., Curry, Joshua N., McCormick, James A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882447/
https://ncbi.nlm.nih.gov/pubmed/24133122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00211.2013
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