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A SPAK isoform switch modulates renal salt transport and blood pressure
The renal thick ascending limb (TAL) and distal convoluted tubule (DCT) play central roles in salt homeostasis and blood pressure regulation. An emerging model suggests that bumetanide and thiazide-sensitive NaCl transporters (NKCC2 and NCC) along these segments are phosphorylated and activated by W...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172576/ https://ncbi.nlm.nih.gov/pubmed/21907141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.07.009 |
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